8X2F

Cryo-EM structure of H5 hemagglutinin from human-infecting H5N8 influenza virus in complex with Sialyl-Lewis X

Summary for 8X2F

• Entry DOI: 10.2210/pdb8x2f/pdb
• EMDB information: 38008
• Descriptor: Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: viral protein-immune system complex, viral protein/immune system
• Biological source: Influenza A virus
• Total number of polymer chains: 3
• Total formula weight: 178347.67

Authors

Jin, X.Y.,Han, P.,Song, H.,Qi, J.X. (deposition date: 2023-11-09, release date: 2025-05-14)

• Primary citation: Jin, X.,Han, P.,Zhang, C.,Maio, A.D.,Shi, Y.,Qi, J.,Bi, Y.,Liu, Y.,Song, H.,Gao, G.F.; Enhanced binding of Sialyl Lewis X to hemagglutinin contributes to H5N8 mammalian pathogenicity and infectivity; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.62 Å)