8X26

Crystal structure of H5 hemagglutinin from human-infecting H5N8 influenza virus in complex with LSTa

Summary for 8X26

• Entry DOI: 10.2210/pdb8x26/pdb
• Descriptor: Hemagglutinin, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, ... (4 entities in total)
• Functional Keywords: viral protein-immune system complex, viral protein/immune system
• Biological source: Influenza A virus
• Total number of polymer chains: 6
• Total formula weight: 353527.26

Authors

Jin, X.Y.,Song, H.,Han, P.,Qi, J.X. (deposition date: 2023-11-09, release date: 2025-05-14, Last modification date: 2025-05-28)

• Primary citation: Jin, X.,Han, P.,Zhang, C.,Maio, A.D.,Shi, Y.,Qi, J.,Bi, Y.,Liu, Y.,Song, H.,Gao, G.F.; Enhanced binding of Sialyl Lewis X to hemagglutinin contributes to H5N8 mammalian pathogenicity and infectivity; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.12 Å)