8WZ4

Cryo-EM structure of prefusion-stabilized RSV F (DS-Cav1 strain: A2) in complex with nAb 5B11 (localized refinement)

Summary for 8WZ4

Entry DOI	10.2210/pdb8wz4/pdb
EMDB information	37946
Descriptor	RSV Fusion glycoprotein, 5B11 Fab Heavy Chain, 5B11 Fab Light Chain (3 entities in total)
Functional Keywords	antibody, viral protein
Biological source	Human respiratory syncytial virus A2 More
Total number of polymer chains	3
Total formula weight	79202.92
Authors	Liu, L.,Sun, H.,Sun, Y.,Zheng, Q.,Li, S.,Zheng, Z.,Xia, N. (deposition date: 2023-11-01, release date: 2024-11-06, Last modification date: 2025-05-28)
Primary citation	Sun, Y.,Liu, L.,Qiang, H.,Sun, H.,Jiang, Y.,Ren, L.,Jiang, Z.,Lei, S.,Chen, L.,Wang, Y.,Lin, X.,Wang, G.,Huang, Y.,Fu, Y.,Shi, Y.,Chen, X.,Yu, H.,Li, S.,Luo, W.,Liu, E.,Zheng, Q.,Zheng, Z.,Xia, N. A potent broad-spectrum neutralizing antibody targeting a conserved region of the prefusion RSV F protein Nat Commun, 15:10085-, 2024 Cited by DOI: 10.1038/s41467-024-54384-x PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.13 Å)

Structure validation