8WWY

Crystal structure of mouse TIFA/TIFAB heterodimer

8WWY の概要

• エントリーDOI: 10.2210/pdb8wwy/pdb
• 分子名称: TRAF-interacting protein with FHA domain-containing protein A, TRAF-interacting protein with FHA domain-containing protein B, (2R,5R)-hexane-2,5-diol, ... (4 entities in total)
• 機能のキーワード: complex, signaling protein
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 67962.50

構造登録者

Nakamura, T. (登録日: 2023-10-27, 公開日: 2024-03-13)

• 主引用文献: Nakamura, T.,Ohyama, C.,Sakamoto, M.,Toma, T.,Tateishi, H.,Matsuo, M.,Chirifu, M.,Ikemizu, S.,Morioka, H.,Fujita, M.,Inoue, J.I.,Yamagata, Y.; TIFAB regulates the TIFA-TRAF6 signaling pathway involved in innate immunity by forming a heterodimer complex with TIFA.; Proc.Natl.Acad.Sci.USA, 121:e2318794121-e2318794121, 2024; PubMed: 38442163; DOI: 10.1073/pnas.2318794121

実験手法

X-RAY DIFFRACTION (1.79 Å)