8WUE
The sigma-1 receptor from Xenopus laevis in complex with dehydroepiandrosterone sulfate by soaking (C2 form)
Summary for 8WUE
Entry DOI | 10.2210/pdb8wue/pdb |
Related | 8W4B 8W4C 8W4D 8W4E 8WWB |
Descriptor | Sigma non-opioid intracellular receptor 1, 17-oxoandrost-5-en-3beta-yl hydrogen sulfate (2 entities in total) |
Functional Keywords | sigma receptor, s1r, endogenous ligand, neurosteroid, dheas, membrane protein |
Biological source | Xenopus laevis (African clawed frog) |
Total number of polymer chains | 6 |
Total formula weight | 156532.86 |
Authors | |
Primary citation | Fu, C.,Xiao, Y.,Zhou, X.,Sun, Z. Insight into binding of endogenous neurosteroid ligands to the sigma-1 receptor. Nat Commun, 15:5619-5619, 2024 Cited by PubMed: 38965213DOI: 10.1038/s41467-024-49894-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.089 Å) |
Structure validation
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