8WUE
The sigma-1 receptor from Xenopus laevis in complex with dehydroepiandrosterone sulfate by soaking (C2 form)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0005635 | cellular_component | nuclear envelope |
| A | 0005637 | cellular_component | nuclear inner membrane |
| A | 0005640 | cellular_component | nuclear outer membrane |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005789 | cellular_component | endoplasmic reticulum membrane |
| A | 0006869 | biological_process | lipid transport |
| A | 0016020 | cellular_component | membrane |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
| B | 0005634 | cellular_component | nucleus |
| B | 0005635 | cellular_component | nuclear envelope |
| B | 0005637 | cellular_component | nuclear inner membrane |
| B | 0005640 | cellular_component | nuclear outer membrane |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0005789 | cellular_component | endoplasmic reticulum membrane |
| B | 0006869 | biological_process | lipid transport |
| B | 0016020 | cellular_component | membrane |
| B | 0031410 | cellular_component | cytoplasmic vesicle |
| C | 0005634 | cellular_component | nucleus |
| C | 0005635 | cellular_component | nuclear envelope |
| C | 0005637 | cellular_component | nuclear inner membrane |
| C | 0005640 | cellular_component | nuclear outer membrane |
| C | 0005783 | cellular_component | endoplasmic reticulum |
| C | 0005789 | cellular_component | endoplasmic reticulum membrane |
| C | 0006869 | biological_process | lipid transport |
| C | 0016020 | cellular_component | membrane |
| C | 0031410 | cellular_component | cytoplasmic vesicle |
| D | 0005634 | cellular_component | nucleus |
| D | 0005635 | cellular_component | nuclear envelope |
| D | 0005637 | cellular_component | nuclear inner membrane |
| D | 0005640 | cellular_component | nuclear outer membrane |
| D | 0005783 | cellular_component | endoplasmic reticulum |
| D | 0005789 | cellular_component | endoplasmic reticulum membrane |
| D | 0006869 | biological_process | lipid transport |
| D | 0016020 | cellular_component | membrane |
| D | 0031410 | cellular_component | cytoplasmic vesicle |
| E | 0005634 | cellular_component | nucleus |
| E | 0005635 | cellular_component | nuclear envelope |
| E | 0005637 | cellular_component | nuclear inner membrane |
| E | 0005640 | cellular_component | nuclear outer membrane |
| E | 0005783 | cellular_component | endoplasmic reticulum |
| E | 0005789 | cellular_component | endoplasmic reticulum membrane |
| E | 0006869 | biological_process | lipid transport |
| E | 0016020 | cellular_component | membrane |
| E | 0031410 | cellular_component | cytoplasmic vesicle |
| F | 0005634 | cellular_component | nucleus |
| F | 0005635 | cellular_component | nuclear envelope |
| F | 0005637 | cellular_component | nuclear inner membrane |
| F | 0005640 | cellular_component | nuclear outer membrane |
| F | 0005783 | cellular_component | endoplasmic reticulum |
| F | 0005789 | cellular_component | endoplasmic reticulum membrane |
| F | 0006869 | biological_process | lipid transport |
| F | 0016020 | cellular_component | membrane |
| F | 0031410 | cellular_component | cytoplasmic vesicle |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | TOPO_DOM: Lumenal => ECO:0000250|UniProtKB:Q99720 |
| Chain | Residue | Details |
| A | MET1-TRP4 | |
| B | MET1-TRP4 | |
| C | MET1-TRP4 | |
| D | MET1-TRP4 | |
| E | MET1-TRP4 | |
| F | MET1-TRP4 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 132 |
| Details | TRANSMEM: Helical => ECO:0000250|UniProtKB:Q99720 |
| Chain | Residue | Details |
| A | LEU5-LEU27 | |
| B | LEU5-LEU27 | |
| C | LEU5-LEU27 | |
| D | LEU5-LEU27 | |
| E | LEU5-LEU27 | |
| F | LEU5-LEU27 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1158 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000250|UniProtKB:Q99720 |
| Chain | Residue | Details |
| A | SER28-PHE221 | |
| B | SER28-PHE221 | |
| C | SER28-PHE221 | |
| D | SER28-PHE221 | |
| E | SER28-PHE221 | |
| F | SER28-PHE221 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | SITE: Important for ligand binding => ECO:0000250|UniProtKB:Q99720 |
| Chain | Residue | Details |
| A | ASP123 | |
| E | GLU169 | |
| F | ASP123 | |
| F | GLU169 | |
| A | GLU169 | |
| B | ASP123 | |
| B | GLU169 | |
| C | ASP123 | |
| C | GLU169 | |
| D | ASP123 | |
| D | GLU169 | |
| E | ASP123 |
