8WTF

The Crystal Structure of IRAK4 from Biortus

Summary for 8WTF

• Entry DOI: 10.2210/pdb8wtf/pdb
• Descriptor: Interleukin-1 receptor-associated kinase 4, 1-{[(2S,3S,4S)-3-ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: kinase, serine/threonine-protein kinase, transferase, immunity, innate immunity, atp-binding, magnesium, nucleotide-binding, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 33956.51

Authors

Wang, F.,Cheng, W.,Lv, Z.,Meng, Q.,Xu, Y. (deposition date: 2023-10-18, release date: 2023-11-15)

• Primary citation: Wang, F.,Cheng, W.,Lv, Z.,Meng, Q.,Xu, Y.; The Crystal Structure of IRAK4 from Biortus; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)