8WST

Cryo-EM structure of Melanin-Concentrating Hormone Receptor 2 with MCH

8WST の概要

• エントリーDOI: 10.2210/pdb8wst/pdb
• EMDBエントリー: 37824
• 分子名称: Guanine nucleotide-binding protein G(q) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• 機能のキーワード: melanin-concentrating hormone receptors2, gpcr, membrane protein
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 128821.24

構造登録者

Zhao, L.,He, Q.,Yuan, Q.,Gu, Y.,Shan, H.,Hu, W.,Wu, K.,Xu, H.E.,Zhang, Y.,Wu, C. (登録日: 2023-10-17, 公開日: 2024-06-19, 最終更新日: 2024-06-26)

• 主引用文献: He, Q.,Yuan, Q.,Shan, H.,Wu, C.,Gu, Y.,Wu, K.,Hu, W.,Zhang, Y.,He, X.,Xu, H.E.,Zhao, L.H.; Mechanisms of ligand recognition and activation of melanin-concentrating hormone receptors.; Cell Discov, 10:48-48, 2024; PubMed: 38710677; DOI: 10.1038/s41421-024-00679-8

実験手法

ELECTRON MICROSCOPY (2.4 Å)