8WRO

XBB.1.5.10 spike protein in complex with ACE2

Summary for 8WRO

Entry DOI	10.2210/pdb8wro/pdb
EMDB information	37784
Descriptor	Spike glycoprotein,Spike glycoprotein,Spike glycoprotein,Fusion protein, Processed angiotensin-converting enzyme 2 (2 entities in total)
Functional Keywords	sars-cov-2, xbb.1.5.10, ace2, spike protein, viral protein/hydrolase, viral protein-hydrolase complex
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	4
Total formula weight	506629.15
Authors	Feng, L.L.,Feng, L.L. (deposition date: 2023-10-15, release date: 2023-12-06, Last modification date: 2024-03-20)
Primary citation	Jian, F.,Feng, L.,Yang, S.,Yu, Y.,Wang, L.,Song, W.,Yisimayi, A.,Chen, X.,Xu, Y.,Wang, P.,Yu, L.,Wang, J.,Liu, L.,Niu, X.,Wang, J.,Xiao, T.,An, R.,Wang, Y.,Gu, Q.,Shao, F.,Jin, R.,Shen, Z.,Wang, Y.,Wang, X.,Cao, Y. Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding. Plos Pathog., 19:e1011868-e1011868, 2023 Cited by PubMed: 38117863 DOI: 10.1371/journal.ppat.1011868 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.9 Å)

Structure validation