8WRO
XBB.1.5.10 spike protein in complex with ACE2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C | Spike glycoprotein,Spike glycoprotein,Spike glycoprotein,Fusion protein | polymer | 1318 | 145941.6 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
2 | D | Processed angiotensin-converting enzyme 2 | polymer | 594 | 68804.3 | 1 | UniProt (Q9BYF1) Pfam (PF01401) In PDB | Homo sapiens (human) |
Sequence modifications
A, B, C: 1 - 1205 (UniProt: P0DTC2)
A, B, C: 1206 - 1318 (PDB: 8WRO)
PDB | External Database | Details |
---|---|---|
Ile 19 | Thr 19 | variant |
- | Leu 24 | deletion |
- | Pro 25 | deletion |
- | Pro 26 | deletion |
Ser 24 | Ala 27 | variant |
Ala 80 | Val 83 | variant |
Asp 139 | Gly 142 | variant |
Gln 143 | His 146 | variant |
Glu 180 | Gln 183 | variant |
Glu 210 | Val 213 | variant |
Val 249 | Gly 252 | variant |
His 336 | Gly 339 | variant |
Thr 343 | Arg 346 | variant |
Ile 365 | Leu 368 | variant |
Phe 368 | Ser 371 | variant |
Pro 370 | Ser 373 | variant |
Phe 372 | Ser 375 | variant |
Ala 373 | Thr 376 | variant |
Asn 402 | Asp 405 | variant |
Ser 405 | Arg 408 | variant |
Asn 414 | Lys 417 | variant |
Lys 437 | Asn 440 | variant |
Pro 442 | Val 445 | variant |
Ser 443 | Gly 446 | variant |
Leu 453 | Phe 456 | variant |
Lys 457 | Asn 460 | variant |
Asn 474 | Ser 477 | variant |
Lys 475 | Thr 478 | variant |
Ala 481 | Glu 484 | variant |
Pro 483 | Phe 486 | conflict |
Ser 487 | Phe 490 | variant |
Arg 495 | Gln 498 | variant |
Tyr 498 | Asn 501 | variant |
His 502 | Tyr 505 | variant |
Gly 611 | Asp 614 | variant |
Tyr 652 | His 655 | variant |
Lys 676 | Asn 679 | variant |
His 678 | Pro 681 | variant |
Gly 679 | Arg 682 | conflict |
Ser 680 | Arg 683 | conflict |
Ser 682 | Arg 685 | conflict |
Lys 761 | Asn 764 | variant |
Tyr 793 | Asp 796 | variant |
Pro 814 | Phe 817 | conflict |
Thr 826 | Ala 829 | conflict |
Lys 833 | Gln 836 | conflict |
Pro 889 | Ala 892 | conflict |
Pro 896 | Ala 899 | conflict |
Pro 939 | Ala 942 | conflict |
His 951 | Gln 954 | variant |
Lys 966 | Asn 969 | variant |
Pro 983 | Lys 986 | variant |
Pro 984 | Val 987 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 506629.2 | |
All* | Total formula weight | 506629.2 |