8WO3

Crystal structure of H. pylori isoleucyl-tRNA synthetase (HpIleRS) in complex with Mupirocin

Summary for 8WO3

• Entry DOI: 10.2210/pdb8wo3/pdb
• Related: 8WNF
• Descriptor: Isoleucine--tRNA ligase, ZINC ION, GLYCEROL, ... (6 entities in total)
• Functional Keywords: isoleucyl-trna synthetase, helicobacter pylori, hpilers, ilers, aminoacylation, ligase
• Biological source: Helicobacter pylori (Campylobacter pylori)
• Total number of polymer chains: 1
• Total formula weight: 107221.97

Authors

Guo, Y.,Li, S.,Zhang, T. (deposition date: 2023-10-06, release date: 2024-02-14, Last modification date: 2024-03-27)

• Primary citation: Chen, X.,Guo, Y.,Shi, J.,Wang, Y.,Guo, X.,Wu, G.,Li, S.,Zhang, T.; Structural basis for substrate and antibiotic recognition by Helicobacter pylori isoleucyl-tRNA synthetase.; Febs Lett., 598:521-536, 2024; PubMed: 38246751; DOI: 10.1002/1873-3468.14805

Experimental method

X-RAY DIFFRACTION (2.2 Å)