8WLK
Cryo-EM structure of human VMAT2 in presence of Tetrabenazine, determined in an outward-facing conformation
Summary for 8WLK
Entry DOI | 10.2210/pdb8wlk/pdb |
EMDB information | 37622 |
Descriptor | Synaptic vesicular amine transporter, (3S,5R,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one (2 entities in total) |
Functional Keywords | human vmat2, tetrabenazine, outward-facing conformation, transport protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 54140.61 |
Authors | |
Primary citation | Qu, Q.,Wang, Y.,Zhou, Z. Cryo-EM structure of human apo VMAT2 in an outward-facing conformation To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3.37 Å) |
Structure validation
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