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8WGV

BA.2(S375) Spike (S6P)/hACE2 complex

Summary for 8WGV
Entry DOI10.2210/pdb8wgv/pdb
EMDB information37516
DescriptorSpike glycoprotein, Angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywordscomplex, viral protein/hydrolase, viral protein-hydrolase complex
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
More
Total number of polymer chains6
Total formula weight639705.00
Authors
Wei, X.,Zhang, Z. (deposition date: 2023-09-22, release date: 2024-02-28, Last modification date: 2024-04-24)
Primary citationHe, X.,Zhang, X.,Wu, B.,Deng, J.,Zhang, Y.,Zhu, A.,Yuan, Y.,Lin, Y.,Chen, A.,Feng, J.,Wang, X.,Wu, S.,Liu, Y.,Liu, J.,Wang, Y.,Li, R.,Liang, C.,Yuan, Q.,Liang, Y.,Fang, Q.,Xi, Z.,Li, W.,Liang, L.,Zhang, Z.,Tang, H.,Peng, Y.,Ke, C.,Ma, X.,Cai, W.,Pan, T.,Liu, B.,Deng, K.,Chen, J.,Zhao, J.,Wei, X.,Chen, R.,Zhang, Y.,Zhang, H.
The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis.
Nat.Immunol., 25:622-632, 2024
Cited by
PubMed: 38454157
DOI: 10.1038/s41590-024-01776-2
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (2.92 Å)
Structure validation

222624

數據於2024-07-17公開中

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