8WG5

Cryo-EM structure of USP16 bound to H2AK119Ub nucleosome

Summary for 8WG5

• Entry DOI: 10.2210/pdb8wg5/pdb
• EMDB information: 37503
• Descriptor: Ubiquitin carboxyl-terminal hydrolase 16, Histone H3.1, Histone H4, ... (8 entities in total)
• Functional Keywords: nucleosome complex, usp16, h2ak119ub, nuclear protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 279465.57

Authors

Ai, H.S.,He, Z.Z.,Deng, Z.H.,Liu, L. (deposition date: 2023-09-20, release date: 2023-12-27, Last modification date: 2024-07-10)

• Primary citation: Ai, H.,He, Z.,Deng, Z.,Chu, G.C.,Shi, Q.,Tong, Z.,Li, J.B.,Pan, M.,Liu, L.; Structural and mechanistic basis for nucleosomal H2AK119 deubiquitination by single-subunit deubiquitinase USP16.; Nat.Struct.Mol.Biol., 2024; PubMed: 38918638; DOI: 10.1038/s41594-024-01342-2

Experimental method

ELECTRON MICROSCOPY (3.05 Å)