8W8H
2-Ketoglutarate-Dependent Dioxygenase
Summary for 8W8H
| Entry DOI | 10.2210/pdb8w8h/pdb |
| Descriptor | 2OG-Fe dioxygenase family protein, ISOLEUCINE (2 entities in total) |
| Functional Keywords | tetramer, metalloenzyme, hydroxylation activity, oxidoreductase |
| Biological source | Bacillus licheniformis |
| Total number of polymer chains | 4 |
| Total formula weight | 119737.66 |
| Authors | Zheng, C.N.,Wei, W.Q. (deposition date: 2023-09-02, release date: 2024-09-04, Last modification date: 2025-09-17) |
| Primary citation | Zheng, C.,Wei, W.,Wen, J.,Song, W.,Wu, J.,Wang, R.,Yin, D.,Chen, X.,Gao, C.,Liu, J.,Liu, L. Rational Design of the Spatial Effect in a Fe(II)/ alpha-Ketoglutarate-Dependent Dioxygenase Reverses the Regioselectivity of C(sp3)-H Bond Hydroxylation in Aliphatic Amino Acids Angew.Chem.Int.Ed.Engl., 63:-, 2024 Cited by DOI: 10.1002/anie.202406060PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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