8W7H

Purine Nucleoside Phosphorylase in complex with MMV000848

8W7H の概要

• エントリーDOI: 10.2210/pdb8w7h/pdb
• 分子名称: Purine nucleoside phosphorylase, (2R)-1-(9H-carbazol-9-yl)-3-(cyclopentylamino)propan-2-ol, 1,2-ETHANEDIOL, ... (6 entities in total)
• 機能のキーワード: protein binding, transferase-inhibitor complex, transferase/inhibitor
• 由来する生物種: Plasmodium falciparum 3D7
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28302.55

構造登録者

Chung, Z.,Lin, J.Q.,Lescar, J. (登録日: 2023-08-30, 公開日: 2024-01-17, 最終更新日: 2024-01-31)

• 主引用文献: Chung, Z.,Lin, J.,Wirjanata, G.,Dziekan, J.M.,El Sahili, A.,Preiser, P.R.,Bozdech, Z.,Lescar, J.; Identification and structural validation of purine nucleoside phosphorylase from Plasmodium falciparum as a target of MMV000848.; J.Biol.Chem., 300:105586-105586, 2023; PubMed: 38141766; DOI: 10.1016/j.jbc.2023.105586

実験手法

X-RAY DIFFRACTION (1.85 Å)