8W4N
Crystal structure of EndoSz mutant D234M, in space group P21, in complex with oligosaccharide G2S1
Summary for 8W4N
Entry DOI | 10.2210/pdb8w4n/pdb |
Related | 8W4K |
Descriptor | Glycoside hydrolase, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION (3 entities in total) |
Functional Keywords | n-linked glycan, glycoside hydrolase, transglycosylation, hydrolase |
Biological source | Streptococcus equi subsp. zooepidemicus Sz105 |
Total number of polymer chains | 1 |
Total formula weight | 112345.54 |
Authors | Guan, H.H.,Lin, C.C.,Hsieh, Y.C.,Chen, C.J. (deposition date: 2023-08-24, release date: 2024-07-03, Last modification date: 2024-07-10) |
Primary citation | Hsieh, Y.C.,Guan, H.H.,Lin, C.C.,Huang, T.Y.,Chuankhayan, P.,Chen, N.C.,Wang, N.H.,Hu, P.L.,Tsai, Y.C.,Huang, Y.C.,Yoshimura, M.,Lin, P.J.,Hsieh, Y.H.,Chen, C.J. Structure-Based High-Efficiency Homogeneous Antibody Platform by Endoglycosidase Sz Provides Insights into Its Transglycosylation Mechanism. Jacs Au, 4:2130-2150, 2024 Cited by PubMed: 38938812DOI: 10.1021/jacsau.4c00004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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