8W34
HIV-1 intasome core assembled with wild-type integrase, 1F
Summary for 8W34
Entry DOI | 10.2210/pdb8w34/pdb |
Related | 8W09 8W2R |
EMDB information | 43761 |
Descriptor | Integrase, DNA (5'-D(*AP*CP*TP*GP*CP*TP*AP*GP*AP*GP*AP*TP*TP*TP*TP*CP*CP*AP*C)-3'), DNA (5'-D(P*GP*TP*GP*GP*AP*AP*AP*AP*TP*CP*TP*CP*TP*AP*GP*CP*A)-3'), ... (6 entities in total) |
Functional Keywords | hiv-1, integrase, nucleoprotein complexes, insti, intasome, cryoem, viral protein |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 12 |
Total formula weight | 330516.87 |
Authors | Li, M.,Craigie, R. (deposition date: 2024-02-21, release date: 2024-04-17, Last modification date: 2024-04-24) |
Primary citation | Li, M.,Yang, R.,Chen, X.,Wang, H.,Ghirlando, R.,Dimitriadis, E.K.,Craigie, R. HIV-1 Integrase Assembles Multiple Species of Stable Synaptic Complex Intasomes That Are Active for Concerted DNA Integration In vitro. J.Mol.Biol., 436:168557-168557, 2024 Cited by PubMed: 38582148DOI: 10.1016/j.jmb.2024.168557 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.83 Å) |
Structure validation
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