8VZK
Crystal Structure of 2-Hydroxyacyl-CoA Lyase/Synthase CfhHACS from Chloroflexi bacterium in the Complex with THDP and ADP
Summary for 8VZK
Entry DOI | 10.2210/pdb8vzk/pdb |
Descriptor | Oxalyl-CoA decarboxylase, THIAMINE DIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... (7 entities in total) |
Functional Keywords | 2-hydroxyacyl-coa lyase/synthase, oxalyly-coa decarboxylase, acyloin condensation, structural biology center, eberlight, lyase |
Biological source | Chloroflexi bacterium HGW-Chloroflexi-9 |
Total number of polymer chains | 2 |
Total formula weight | 122575.22 |
Authors | Kim, Y.,Gade, P.,Mayfield, A.,Endres, M.,Lee, S.,Yoshikuni, Y.,Gonzalez, R.,Michalska, K.,Joachimiak, A. (deposition date: 2024-02-11, release date: 2024-10-02) |
Primary citation | Kim, Y.,Lee, S.H.,Gade, P.,Nattermann, M.,Maltseva, N.,Endres, M.,Chen, J.,Wichmann, P.,Hu, Y.,Marchal, D.G.,Yoshikuni, Y.,Erb, T.J.,Gonzalez, R.,Michalska, K.,Joachimiak, A. Revealing reaction intermediates in one-carbon elongation by thiamine diphosphate/CoA-dependent enzyme family. Commun Chem, 7:160-160, 2024 Cited by PubMed: 39034323DOI: 10.1038/s42004-024-01242-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
Download full validation report