8VWW

CCHFV GP38 bound to ADI-46152 and ADI-58048 Fabs

Summary for 8VWW

• Entry DOI: 10.2210/pdb8vww/pdb
• EMDB information: 43604
• Descriptor: GP38, ADI-46152 Fab Heavy Chain, ADI-46152 Fab Light Chain, ... (5 entities in total)
• Functional Keywords: cchfv, gp38, antibody, immunology, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Crimean-Congo hemorrhagic fever virus strain IbAr10200; More
• Total number of polymer chains: 5
• Total formula weight: 124726.16

Authors

Hjorth, C.K.,McLellan, J.S. (deposition date: 2024-02-02, release date: 2024-07-24)

• Primary citation: Shin, O.S.,Monticelli, S.R.,Hjorth, C.K.,Hornet, V.,Doyle, M.,Abelson, D.,Kuehne, A.I.,Wang, A.,Bakken, R.R.,Mishra, A.K.,Middlecamp, M.,Champney, E.,Stuart, L.,Maurer, D.P.,Li, J.,Berrigan, J.,Barajas, J.,Balinandi, S.,Lutwama, J.J.,Lobel, L.,Zeitlin, L.,Walker, L.M.,Dye, J.M.,Chandran, K.,Herbert, A.S.,Pauli, N.T.,McLellan, J.S.; Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38.; Cell Rep, 43:114502-114502, 2024; PubMed: 39002130; DOI: 10.1016/j.celrep.2024.114502

Experimental method

ELECTRON MICROSCOPY (3.9 Å)