8VV1

Estrogen receptor alpha ligand binding domain in complex with palazestrant

This is a non-PDB format compatible entry.

Summary for 8VV1

• Entry DOI: 10.2210/pdb8vv1/pdb
• Descriptor: Estrogen receptor, palazestrant, GLYCEROL, ... (4 entities in total)
• Functional Keywords: estrogen receptor, ceran, ligand binding domain, alpha helical bundle, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 57701.71

Authors

Ng, R.A.,Barratt, S.,Parisian, A.,Palanisamy, G.,Sun, R.,Robello, B.,Pena, G.,Sapugay, J.,Yeghikyan, D.,Duncan, A.,Andersen, S.E.,Chawla, R.,Rich, B.,Hearn, B.,Harmon, C.,Hodges-Gallagher, L.,Kushner, P.J.,Greene, G.L.,Myles, D.C.,Fanning, S.W. (deposition date: 2024-01-30, release date: 2025-03-19)

• Primary citation: Fanning, S.W.; Estrogen receptor alpha ligand binding domain in complex with palazestrant; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.196 Å)