8VU3

Cryo-EM structure of cyanobacterial PSI with bound platinum nanoparticles

Summary for 8VU3

• Entry DOI: 10.2210/pdb8vu3/pdb
• EMDB information: 43525
• Descriptor: Photosystem I P700 chlorophyll a apoprotein A1, Photosystem I reaction center subunit XI, Photosystem I reaction center subunit XII, ... (20 entities in total)
• Functional Keywords: photosynthesis, cyanobacteria, biohybrid, platinum nanoparticles, hydrogen production, photosystem i, solar fuel
• Biological source: Thermostichus lividus; More
• Total number of polymer chains: 36
• Total formula weight: 1079914.25

Authors

Gisriel, C.J.,Malavath, T.,Brudvig, G.W.,Utschig, L.M. (deposition date: 2024-01-28, release date: 2024-10-30, Last modification date: 2025-05-14)

Primary citation

Gisriel, C.J.,Malavath, T.,Qiu, T.,Menzel, J.P.,Batista, V.S.,Brudvig, G.W.,Utschig, L.M.
Structure of a biohybrid photosystem I-platinum nanoparticle solar fuel catalyst.
Nat Commun, 15:9519-9519, 2024

PubMed Abstract: Biohybrid solar fuel catalysts leverage natural light-driven enzymes to produce valuable fuel products. One useful biological platform for such a system is photosystem I, a pigment-protein complex that captures sunlight and converts it into chemical energy with near unity quantum efficiency, which generates low potential reducing equivalents for metabolism. Realizing and understanding the molecular basis for an approach that utilizes those electrons and stores solar energy as a fuel is therefore appealing. Here, we report the 2.27-Å global resolution cryo-EM structure of a photosystem I complex with bound platinum nanoparticles that catalyzes light-driven H production. The platinum nanoparticle binding sites and possible stabilizing interactions are described. Overall, the investigation reveals a direct structural look at a photon-to-fuels photosynthetic biohybrid system.

PubMed: 39496605
DOI: 10.1038/s41467-024-53476-y

Experimental method

ELECTRON MICROSCOPY (2.27 Å)