8VTC

Crystal structure of Mycobacterium avium dihydrofolate reductase in complex with NADPH and trimethoprim

8VTC の概要

• エントリーDOI: 10.2210/pdb8vtc/pdb
• 分子名称: Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TRIMETHOPRIM, ... (5 entities in total)
• 機能のキーワード: dihydrofolate reductase, mycobacterium avium, trimetoprim, oxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• 由来する生物種: Mycobacterium avium
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 19523.01

構造登録者

Erlandsen, H.,Krucinska, J.,Wright, D. (登録日: 2024-01-26, 公開日: 2025-03-19)

• 主引用文献: Wright, L.,Krucinska, J.,Erlandsen, H.,Haijan, B.,Cynamon, M.,Wright, D.; Long Residence Time Inhibitors of Dihydrofolate Reductase Display Potent Activity Against Mycobacterium Avium.; To Be Published,

実験手法

X-RAY DIFFRACTION (2 Å)