8VS0

A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds

This is a non-PDB format compatible entry.

Summary for 8VS0

• Entry DOI: 10.2210/pdb8vs0/pdb
• Descriptor: Mitogen-activated protein kinase 10, (4P)-4-[6-fluoro-5-(2-methoxyanilino)-1H-indazol-1-yl]-5-methyl-N-(oxetan-3-yl)thiophene-2-carboxamide (3 entities in total)
• Functional Keywords: c-jun terminal kinase 3, jnk3, p38 alpha, kinase, selectivity, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 53101.83

Authors

Park, H.,Feng, Y. (deposition date: 2024-01-23, release date: 2025-01-29)

• Primary citation: Park, H.,Feng, Y.; A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.46 Å)