8VQ6

hCA-II-4-(2-Aminoethyl)benzenesulfonamide-complex. Two molecules of inhibitor bound to active site and secondary binding pocket

Summary for 8VQ6

• Entry DOI: 10.2210/pdb8vq6/pdb
• Related: 8VQ5 8VQ7
• Descriptor: Carbonic anhydrase 2, ZINC ION, 4-(2-AMINOETHYL)BENZENESULFONAMIDE, ... (4 entities in total)
• Functional Keywords: carbonic anhydrase ii, human carbonic anhydrase ii, carbon anhydrase, two pockets bound, binding pocket, binding pockets, active site, small molecule, bivalent, complex, protein ligand complex, protein inhibition, inhibitor, binder, nano molar binder, nano molar inhibitor, protein binding, 4-(2-aminoethyl)benzenesulfonamide, secondary binding site, zyx, lyase-inhibitor complex, lyase/inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 29955.25

Authors

Ismail, M.M. (deposition date: 2024-01-17, release date: 2025-07-16)

• Primary citation: Ismail, M.M.; SBDD of Carbonic Anhydrase II Inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.45 Å)