8VPU

Crystal structure of mouse Importin alpha in complex with dengue virus 3 NS5 central NLS peptide

Summary for 8VPU

• Entry DOI: 10.2210/pdb8vpu/pdb
• Related: 8VPR
• Descriptor: Importin subunit alpha-1, RNA-directed RNA polymerase NS5 central NLS peptide (3 entities in total)
• Functional Keywords: protein transport, viral protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 59768.77

Authors

Roman, N.,Swarbrick, C.M.D.,Forwood, J.K. (deposition date: 2024-01-17, release date: 2024-08-21)

• Primary citation: Cheng, C.X.,Tan, M.J.A.,Chan, K.W.K.,Choy, M.M.J.,Roman, N.,Arnold, D.D.R.,Bifani, A.M.,Kong, S.Y.Z.,Bist, P.,Nath, B.K.,Swarbrick, C.M.D.,Forwood, J.K.,Vasudevan, S.G.; Serotype-Specific Regulation of Dengue Virus NS5 Protein Subcellular Localization.; Acs Infect Dis., 10:2047-2062, 2024; PubMed: 38811007; DOI: 10.1021/acsinfecdis.4c00054

Experimental method

X-RAY DIFFRACTION (2.1 Å)