8VO4

A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds

Summary for 8VO4

• Entry DOI: 10.2210/pdb8vo4/pdb
• Descriptor: Mitogen-activated protein kinase 10, (4P)-4-{6-[(azetidin-1-yl)methyl]-5-(2-chloro-6-fluoroanilino)-1H-indazol-1-yl}-N-methylthiophene-2-carboxamide (3 entities in total)
• Functional Keywords: c-jun terminal kinase 3, jnk3, p38 alpha, kinase, selectivity, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 53119.29

Authors

Park, H.,Feng, Y. (deposition date: 2024-01-14, release date: 2025-01-15)

• Primary citation: Park, H.,Feng, Y.; A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.07 Å)