8VMH

A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds

This is a non-PDB format compatible entry.

Summary for 8VMH

• Entry DOI: 10.2210/pdb8vmh/pdb
• Related: 8EFJ
• Descriptor: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside, (4P)-4-[6-fluoro-5-(2-methoxyanilino)-1H-indazol-1-yl]-5-methyl-N-(oxetan-3-yl)thiophene-2-carboxamide, ... (4 entities in total)
• Functional Keywords: c-jun terminal kinase 3, jnk3, p38 alpha, kinase, selectivity, transferase
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 1
• Total formula weight: 43275.36

Authors

Park, H.,Feng, Y. (deposition date: 2024-01-13, release date: 2025-01-15)

• Primary citation: Park, H.,Feng, Y.; A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.46 Å)