8VL7

Co-crystal structure of human TREX1 in complex with an inhibitor

これはPDB形式変換不可エントリーです。

8VL7 の概要

• エントリーDOI: 10.2210/pdb8vl7/pdb
• 分子名称: Three-prime repair exonuclease 1, (2P)-2-[3-bromo-2-(2-hydroxyethoxy)phenyl]-5-hydroxy-1-methyl-N-(1,2-oxazol-4-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide, GLYCEROL, ... (8 entities in total)
• 機能のキーワード: trex1, inhibitor, nuclease, sgc, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 204847.50

構造登録者

Dehghani-Tafti, S.,Dong, A.,Li, Y.,Ackloo, S.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L. (登録日: 2024-01-11, 公開日: 2024-01-24)

• 主引用文献: Dehghani-Tafti, S.,Dong, A.,Li, Y.,Ackloo, S.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.; Co-crystal structure of human TREX1 in complex with an inhibitor; To be published,

実験手法

X-RAY DIFFRACTION (1.88 Å)