8VHO
Crystal Structure of E. coli class Ia ribonucleotide reductase alpha subunit bound to dATP
Summary for 8VHO
Entry DOI | 10.2210/pdb8vho/pdb |
Related | 8VHN 8VHP 8VHQ 8VHR 8VHU |
Descriptor | Ribonucleoside-diphosphate reductase 1 subunit alpha, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | ribonucleotide reductase, allosteric regulation, nucleotide binding, subunit interaction, oxidoreductase |
Biological source | Escherichia coli K-12 |
Total number of polymer chains | 2 |
Total formula weight | 174390.78 |
Authors | |
Primary citation | Funk, M.A.,Zimanyi, C.M.,Andree, G.A.,Hamilos, A.E.,Drennan, C.L. How ATP and dATP Act as Molecular Switches to Regulate Enzymatic Activity in the Prototypical Bacterial Class Ia Ribonucleotide Reductase. Biochemistry, 2024 Cited by PubMed: 39164005DOI: 10.1021/acs.biochem.4c00329 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.548 Å) |
Structure validation
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