8VHN

Crystal Structure of E. coli class Ia ribonucleotide reductase alpha subunit bound to two ATP molecules

8VHN の概要

• エントリーDOI: 10.2210/pdb8vhn/pdb
• 関連するPDBエントリー: 8VHO 8VHP 8VHQ 8VHR 8VHU
• 分子名称: Ribonucleoside-diphosphate reductase 1 subunit alpha, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total)
• 機能のキーワード: ribonucleotide reductase, allosteric regulation, nucleotide binding, subunit, oxidoreductase
• 由来する生物種: Escherichia coli K-12
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 175469.14

構造登録者

Funk, M.A.,Zimanyi, C.M.,Drennan, C.L. (登録日: 2024-01-02, 公開日: 2024-09-04)

• 主引用文献: Funk, M.A.,Zimanyi, C.M.,Andree, G.A.,Hamilos, A.E.,Drennan, C.L.; How ATP and dATP Act as Molecular Switches to Regulate Enzymatic Activity in the Prototypical Bacterial Class Ia Ribonucleotide Reductase.; Biochemistry, 2024; PubMed: 39164005; DOI: 10.1021/acs.biochem.4c00329

実験手法

X-RAY DIFFRACTION (2.62 Å)