8VEZ

De novo design apixaban-binding protein: apx1049

Summary for 8VEZ

• Entry DOI: 10.2210/pdb8vez/pdb
• Descriptor: De novo design apixaban-binding protein: apx1049, 1-(4-METHOXYPHENYL)-7-OXO-6-[4-(2-OXOPIPERIDIN-1-YL)PHENYL]-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-C]PYRIDINE-3-CARBOXAMIDE (3 entities in total)
• Functional Keywords: protein design, deep learning, small-molecule-binding, de novo design, apixaban, de novo protein
• Biological source: synthetic construct
• Total number of polymer chains: 1
• Total formula weight: 13557.74

Authors

Bera, A.K.,Lee, G.R.,Baker, D. (deposition date: 2023-12-20, release date: 2025-01-15)

• Primary citation: Lee, G.R.,Bera, A.K.,Baker, D.; Small-molecule binding and sensing with a designed protein family; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.15 Å)