8VE4

Unliganded human transthyretin in the frayed conformation

Summary for 8VE4

• Entry DOI: 10.2210/pdb8ve4/pdb
• EMDB information: 43164
• Descriptor: Transthyretin (1 entity in total)
• Functional Keywords: amyloidosis, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 55634.23

Authors

Basanta, B.,Nugroho, K.,Yan, N.,Kline, G.M.,Tsai, F.J.,Wu, M.,Kelly, J.W.,Lander, G.C. (deposition date: 2023-12-18, release date: 2024-06-05)

• Primary citation: Basanta, B.,Nugroho, K.,Yan, N.,Kline, G.M.,Powers, E.T.,Tsai, F.J.,Wu, M.,Hansel-Harris, A.,Chen, J.,Forli, S.,Kelly, J.W.,Lander, G.C.; The conformational landscape of human transthyretin revealed by cryo-EM; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.3 Å)