8VDW

X-Ray Crystal Structure of the biotin synthase from V. parvula

Summary for 8VDW

Entry DOI	10.2210/pdb8vdw/pdb
Related	8VCW
Descriptor	Biotin synthase, Fe4 H S5, S-ADENOSYLMETHIONINE, ... (7 entities in total)
Functional Keywords	radical sam, iron-sulfur cluster, sulfur insertion, 4 iron-5 sulfur cluster, transferase
Biological source	Veillonella parvula
Total number of polymer chains	2
Total formula weight	83696.86
Authors	Lachowicz, J.C.,Grove, T.L. (deposition date: 2023-12-18, release date: 2024-01-24, Last modification date: 2024-02-07)
Primary citation	Lachowicz, J.C.,Lennox-Hvenekilde, D.,Myling-Petersen, N.,Salomonsen, B.,Verkleij, G.,Acevedo-Rocha, C.G.,Caddell, B.,Gronenberg, L.S.,Almo, S.C.,Sommer, M.O.A.,Genee, H.J.,Grove, T.L. Discovery of a Biotin Synthase That Utilizes an Auxiliary 4Fe-5S Cluster for Sulfur Insertion. J.Am.Chem.Soc., 146:1860-1873, 2024 Cited by PubMed: 38215281 DOI: 10.1021/jacs.3c05481 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.807 Å)

Structure validation