8VCG

Mutant Src SH2 domain in complex with phosphotyrosine

Summary for 8VCG

• Entry DOI: 10.2210/pdb8vcg/pdb
• Descriptor: Isoform 3 of Proto-oncogene tyrosine-protein kinase Src, O-PHOSPHOTYROSINE (3 entities in total)
• Functional Keywords: sh2 domain, cell signalling, phosphotyrosine binding, protein binding
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 14581.18

Authors

Hashem, A.,Nyovanie, S.,Oltean, N.,Patskovska, L.,Patskovsky, Y.,Krogsgaard, M. (deposition date: 2023-12-14, release date: 2025-01-29)

• Primary citation: Hashem, A.,Nyovanie, S.,Patskovsky, Y.,Krogsgaard, M.; Engineered Mutant Src Sh2 Domain; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.61 Å)