8V9Q
Crystal structure of mGalNAc-T1 in complex with the mucin glycopeptide Muc5AC-13, Mn2+, and UDP.
Summary for 8V9Q
Entry DOI | 10.2210/pdb8v9q/pdb |
Descriptor | Polypeptide N-acetylgalactosaminyltransferase 1 soluble form, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total) |
Functional Keywords | gt-a fold catalytic domain, lectin domain, golgi membrane, mucin-type o-glycosyltransferase, transferase |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 5 |
Total formula weight | 137158.67 |
Authors | |
Primary citation | Collette, A.M.,Hassan, S.A.,Schmidt, S.I.,Lara, A.J.,Yang, W.,Samara, N.L. An unusual dual sugar-binding lectin domain controls the substrate specificity of a mucin-type O-glycosyltransferase. Sci Adv, 10:eadj8829-eadj8829, 2024 Cited by PubMed: 38416819DOI: 10.1126/sciadv.adj8829 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.29 Å) |
Structure validation
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