8V9Q

Crystal structure of mGalNAc-T1 in complex with the mucin glycopeptide Muc5AC-13, Mn2+, and UDP.

8V9Q の概要

• エントリーDOI: 10.2210/pdb8v9q/pdb
• 分子名称: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (12 entities in total)
• 機能のキーワード: gt-a fold catalytic domain, lectin domain, golgi membrane, mucin-type o-glycosyltransferase, transferase
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 137158.67

構造登録者

Samara, N.L.,Collette, A.M. (登録日: 2023-12-08, 公開日: 2024-03-13)

• 主引用文献: Collette, A.M.,Hassan, S.A.,Schmidt, S.I.,Lara, A.J.,Yang, W.,Samara, N.L.; An unusual dual sugar-binding lectin domain controls the substrate specificity of a mucin-type O-glycosyltransferase.; Sci Adv, 10:eadj8829-eadj8829, 2024; PubMed: 38416819; DOI: 10.1126/sciadv.adj8829

実験手法

X-RAY DIFFRACTION (2.29 Å)