8V79

Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 15

Summary for 8V79

• Entry DOI: 10.2210/pdb8v79/pdb
• Descriptor: Inositol polyphosphate multikinase, (3P,5M)-3-[3-(1-cyclobutylpiperidin-4-yl)phenyl]-5-(1H-tetrazol-5-yl)-2,1-benzoxazole (3 entities in total)
• Functional Keywords: structure-based inhibitor development, kinase, inhibitor, inositol polyphosphate, inositol polyphosphate kinase, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 1
• Total formula weight: 30228.39

Authors

Wang, H.,Shears, S.B. (deposition date: 2023-12-04, release date: 2024-12-11)

• Primary citation: Wang, H.,Shears, S.B.; Structure-based development of IPMK kinase inhibitors.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)