8V5T

Crystal structure of Alzheimers disease phospholipase D3

Summary for 8V5T

• Entry DOI: 10.2210/pdb8v5t/pdb
• Descriptor: 5'-3' exonuclease PLD3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (5 entities in total)
• Functional Keywords: exonuclease, alzheimer's disease, dna binding protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 112452.66

Authors

Ishii, K.,Hermans, S.J.,Nero, T.L.,Gorman, M.A.,Parker, M.W. (deposition date: 2023-12-01, release date: 2024-10-09)

• Primary citation: Ishii, K.,Hermans, S.J.,Georgopoulou, M.E.,Nero, T.L.,Hancock, N.C.,Crespi, G.A.N.,Gorman, M.A.,Gooi, J.H.,Parker, M.W.; Crystal structure of Alzheimer's disease phospholipase D3 provides a molecular basis for understanding its normal and pathological functions.; Febs J., 2024; PubMed: 39325669; DOI: 10.1111/febs.17277

Experimental method

X-RAY DIFFRACTION (2.3 Å)