8V5T
Crystal structure of Alzheimers disease phospholipase D3
Summary for 8V5T
Entry DOI | 10.2210/pdb8v5t/pdb |
Descriptor | 5'-3' exonuclease PLD3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (5 entities in total) |
Functional Keywords | exonuclease, alzheimer's disease, dna binding protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 112452.66 |
Authors | Ishii, K.,Hermans, S.J.,Nero, T.L.,Gorman, M.A.,Parker, M.W. (deposition date: 2023-12-01, release date: 2024-10-09) |
Primary citation | Ishii, K.,Hermans, S.J.,Georgopoulou, M.E.,Nero, T.L.,Hancock, N.C.,Crespi, G.A.N.,Gorman, M.A.,Gooi, J.H.,Parker, M.W. Crystal structure of Alzheimer's disease phospholipase D3 provides a molecular basis for understanding its normal and pathological functions. Febs J., 2024 Cited by PubMed: 39325669DOI: 10.1111/febs.17277 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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