8V5T

Crystal structure of Alzheimers disease phospholipase D3

8V5T の概要

• エントリーDOI: 10.2210/pdb8v5t/pdb
• 分子名称: 5'-3' exonuclease PLD3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: exonuclease, alzheimer's disease, dna binding protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 112452.66

構造登録者

Ishii, K.,Hermans, S.J.,Nero, T.L.,Gorman, M.A.,Parker, M.W. (登録日: 2023-12-01, 公開日: 2024-10-09)

• 主引用文献: Ishii, K.,Hermans, S.J.,Georgopoulou, M.E.,Nero, T.L.,Hancock, N.C.,Crespi, G.A.N.,Gorman, M.A.,Gooi, J.H.,Parker, M.W.; Crystal structure of Alzheimer's disease phospholipase D3 provides a molecular basis for understanding its normal and pathological functions.; Febs J., 2024; PubMed: 39325669; DOI: 10.1111/febs.17277

実験手法

X-RAY DIFFRACTION (2.3 Å)