8V3N
CCP5 in complex with Glu-P-Glu transition state analog
This is a non-PDB format compatible entry.
Summary for 8V3N
Entry DOI | 10.2210/pdb8v3n/pdb |
Descriptor | Cytosolic carboxypeptidase-like protein 5, ZINC ION, D-MALATE, ... (5 entities in total) |
Functional Keywords | carboxypeptidase deglutamylation branch glutamate removal microtubule, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 1 |
Total formula weight | 59884.58 |
Authors | Chen, J.,Zehr, E.A.,Gruschus, J.M.,Szyk, A.,Liu, Y.,Tanner, M.E.,Tjandra, N.,Roll-Mecak, A. (deposition date: 2023-11-28, release date: 2024-07-17, Last modification date: 2024-08-07) |
Primary citation | Chen, J.,Zehr, E.A.,Gruschus, J.M.,Szyk, A.,Liu, Y.,Tanner, M.E.,Tjandra, N.,Roll-Mecak, A. Tubulin code eraser CCP5 binds branch glutamates by substrate deformation. Nature, 631:905-912, 2024 Cited by PubMed: 39020174DOI: 10.1038/s41586-024-07699-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report