8V1L
Crystal structure of the NTF2L domain of human G3BP1 in complex with small molecule
Summary for 8V1L
Entry DOI | 10.2210/pdb8v1l/pdb |
Descriptor | Ras GTPase-activating protein-binding protein 1, N-[(2S)-2-fluoro-4,4-dimethylpentanoyl]-3-hydroxy-L-valyl-(betaS)-beta-methyl-L-phenylalanyl-D-alanyl-N-benzyl-N,O-dimethyl-L-homoserinamide (3 entities in total) |
Functional Keywords | small molecule, complex, ntf2l, g3bp1 faz compound, rna binding protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 6 |
Total formula weight | 99677.73 |
Authors | |
Primary citation | Freibaum, B.D.,Messing, J.,Nakamura, H.,Yurtsever, U.,Wu, J.,Kim, H.J.,Hixon, J.,Lemieux, R.M.,Duffner, J.,Huynh, W.,Wong, K.,White, M.,Lee, C.,Meyers, R.E.,Parker, R.,Taylor, J.P. Identification of small molecule inhibitors of G3BP-driven stress granule formation. J.Cell Biol., 223:-, 2024 Cited by PubMed: 38284934DOI: 10.1083/jcb.202308083 PDB entries with the same primary citation |
Experimental method |
Structure validation
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