8UUQ
Structure of the Measles virus Fusion protein in the pre-fusion conformation with bound [FIP-HRC]2-PEG11
Summary for 8UUQ
Entry DOI | 10.2210/pdb8uuq/pdb |
EMDB information | 42595 |
Related PRD ID | PRD_002539 |
Descriptor | Fusion glycoprotein F0, [FIP-HRC]2-PEG11, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | viral protein, glycoprotein, immune system, measles, high-resolution, ectodomain, post-fusion, small molecule, inhibitor, complex |
Biological source | Measles virus strain Ichinose-B95a More |
Total number of polymer chains | 9 |
Total formula weight | 178534.84 |
Authors | Zyla, D.,Saphire, E.O. (deposition date: 2023-11-01, release date: 2024-07-03, Last modification date: 2024-07-24) |
Primary citation | Zyla, D.S.,Della Marca, R.,Niemeyer, G.,Zipursky, G.,Stearns, K.,Leedale, C.,Sobolik, E.B.,Callaway, H.M.,Hariharan, C.,Peng, W.,Parekh, D.,Marcink, T.C.,Diaz Avalos, R.,Horvat, B.,Mathieu, C.,Snijder, J.,Greninger, A.L.,Hastie, K.M.,Niewiesk, S.,Moscona, A.,Porotto, M.,Ollmann Saphire, E. A neutralizing antibody prevents postfusion transition of measles virus fusion protein. Science, 384:eadm8693-eadm8693, 2024 Cited by PubMed: 38935733DOI: 10.1126/science.adm8693 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.34 Å) |
Structure validation
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