8USJ
Crystal Structure of Kemp Eliminase HG198 with bound transition state analogue, 280 K
Summary for 8USJ
Entry DOI | 10.2210/pdb8usj/pdb |
Descriptor | Kemp eliminase, 6-NITROBENZOTRIAZOLE (3 entities in total) |
Functional Keywords | de novo enzyme design; computational protein design; kemp eliminases; biocatalysis; directed evolution; x-ray crystallography, hydrolase |
Biological source | Thermoascus aurantiacus |
Total number of polymer chains | 3 |
Total formula weight | 103510.83 |
Authors | Seifinoferest, B. (deposition date: 2023-10-27, release date: 2023-12-06, Last modification date: 2024-06-19) |
Primary citation | Rakotoharisoa, R.V.,Seifinoferest, B.,Zarifi, N.,Miller, J.D.M.,Rodriguez, J.M.,Thompson, M.C.,Chica, R.A. Design of Efficient Artificial Enzymes Using Crystallographically Enhanced Conformational Sampling. J.Am.Chem.Soc., 146:10001-10013, 2024 Cited by PubMed: 38532610DOI: 10.1021/jacs.4c00677 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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