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8US8

Crystal structure of B1E11K malarial antibody in complex with RESA repeat peptide

Summary for 8US8
Entry DOI10.2210/pdb8us8/pdb
DescriptorB1E11K Fab A Heavy Chain, B1E11K Fab A Kappa Light Chain, Ring-infected erythrocyte surface antigen peptide, ... (6 entities in total)
Functional Keywordsmalaria, antibody, immune system, homotypic
Biological sourceHomo sapiens (human)
More
Total number of polymer chains5
Total formula weight96592.54
Authors
Yoo, R.,Julien, J.P. (deposition date: 2023-10-27, release date: 2024-10-30)
Primary citationAmen, A.,Yoo, R.,Fabra-Garcia, A.,Sauerwein, R.,MacGill, R.S.,Julien, J.P.,Poignard, P.,Jore, M.M.
Target-agnostic isolation of human monoclonal antibodies against Plasmodium falciparum sexual stage proteins reveals recognition of glutamate-rich repeats through antibody homotypic interactions
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.56 Å)
Structure validation

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