8UQV
Trehalose Synthase (TreS) of Mycobacterium tuberculosis in complex with 6-TreAz compound
Summary for 8UQV
Entry DOI | 10.2210/pdb8uqv/pdb |
EMDB information | 42478 |
Descriptor | Trehalose synthase/amylase TreS, alpha-D-glucopyranose, 6-azido-6-deoxy-alpha-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | tres, trehalose synthase, mycobacterium tuberculosis, 6-treaz, cytosolic protein |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 4 |
Total formula weight | 264871.96 |
Authors | Pathirage, R.,Ronning, D.R. (deposition date: 2023-10-24, release date: 2024-03-27, Last modification date: 2024-04-24) |
Primary citation | Kalera, K.,Liu, R.,Lim, J.,Pathirage, R.,Swanson, D.H.,Johnson, U.G.,Stothard, A.I.,Lee, J.J.,Poston, A.W.,Woodruff, P.J.,Ronning, D.R.,Eoh, H.,Swarts, B.M. Targeting Mycobacterium tuberculosis Persistence through Inhibition of the Trehalose Catalytic Shift. Acs Infect Dis., 10:1391-1404, 2024 Cited by PubMed: 38485491DOI: 10.1021/acsinfecdis.4c00138 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
Download full validation report