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8UQF

Crystal structure of designed cortisol-binding protein hcy129_mpnn5

Summary for 8UQF
Entry DOI10.2210/pdb8uqf/pdb
Descriptordesigned cortisol-binding protein hcy129_mpnn5, (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, SULFATE ION, ... (4 entities in total)
Functional Keywordsntf2, cortisol binding, de novo protein
Biological sourcesynthetic construct
Total number of polymer chains2
Total formula weight31633.83
Authors
Pellock, S.J.,Bera, A. (deposition date: 2023-10-23, release date: 2024-11-20)
Primary citationLee, G.R.,Pellock, S.J.,Norn, C.,Tischer, D.,Dauparas, J.,Anischenko, I.,Mercer, J.A.M.,Kang, A.,Bera, A.,Nguyen, H.,Goreshnik, I.,Vafeados, D.,Roullier, N.,Han, H.L.,Coventry, B.,Liu, D.R.,Yeh, A.H.W.
Small molecule binding and sensing with a designed protein family
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.52 Å)
Structure validation

247947

PDB entries from 2026-01-21

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