8UOL

Crystal structure of human NUAK1-MARK3 (6 mutations) kinase domain chimera bound with small molecule inhibitor #31

Summary for 8UOL

• Entry DOI: 10.2210/pdb8uol/pdb
• Descriptor: MAP/microtubule affinity-regulating kinase 3, Narazaciclib, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: kinase, serine/threonine-protein kinase, nuak1, mark3, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 76977.03

Authors

Delker, S.L.,Abendroth, J. (deposition date: 2023-10-19, release date: 2024-10-23)

• Primary citation: Delker, S.L.,Abendroth, J.; Crystal structure of human NUAK1-MARK3 kinase domain chimera bound with small molecule inhibitor #31; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)