8UMF

Structure of PsCas9 in complex with gRNA and DNA in product state

Summary for 8UMF

• Entry DOI: 10.2210/pdb8umf/pdb
• EMDB information: 42378
• Descriptor: Cas9, RNA (121-MER), DNA (80-MER), ... (5 entities in total)
• Functional Keywords: cas9, crispr, immune system
• Biological source: Parasutterella secunda; More
• Total number of polymer chains: 5
• Total formula weight: 284207.26

Authors

Bravo, J.P.K.,Taylor, D.W. (deposition date: 2023-10-17, release date: 2024-10-02)

• Primary citation: Bravo, J.P.K.,Taylor, D.W.; Structure-guided engineering of PsCas9 yields a high fidelity and activity enzyme for in vivo gene editing; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.9 Å)